Indian Journal of Ayurveda & Research

Proceedings of National Ayurveda Day Celebration and NIRVISHA – 2018 National conference on Agada Tantra

Dr Mahesh P Savalagimath1 , Dr Santosh F Patil 1, Dr R R Hiremath1

Address for correspondence:
Department of  Agada Tantra, KAHER’s Shri B M Kankanwadi Ayurved Mahavidyalaya, Belagavi- 590003, Karnataka, India.
Email-id: dr.santosh19@gmail.com

 How to cite this article: Savalagimath M. P., Patil S. F. , Hiremath R. R. Proceedings of Ayurveda Day Celebration and Nirvisha – National Conference on Agada Tantra. Indian J Ayurveda Res 2018;1:67-70

Inauguration by chief guest Ms. Meenakshi Negi, Commissioner, Dept.of AYUSH, Govt. of Karnataka. Guest of Honor Dr. Sanjeev Sharma, Director, National Institute of Ayurveda, Jaipur. President of Function Prof. Dr. Vivek Saoji, Vice Chancellor, KAHER, Belgavi. Dr. V. D Patil, Registrar KAHER. Dr. B. S. Prasad, Principal, KAHER Shri. B M Kankanwadi Ayurved Mahavidyalaya. Dr. Mahesh P. Savalgimath, Organizing Secretary were also present.

Agadatantra, branch of Ayurveda is based on strong principles of toxicology which has elaborated qualities, sources of poisons, its manifestations and treatment thereafter. Emerging trends in Toxicology are becoming warranted with poisons or chemicals that are being used daily can lead to various health issues including autoimmune disorders, genetic exhibitions and not only life threatening. Stakes are high for present toxicological manifestations, based on these principles for treating or preventing them. To bring these adapted principles of toxicology practice under one roof and explore new horizons including legal aspects of Ayurveda practice Shri B M Kankanawadi Ayurved Mahavidyalaya and PG studies, a constituent unit of KLE Academy of Higher Education and Research, Belagavi, Karnataka, hosted NIRVISHA-2018 from 25th to 27th October 2018 as part of NATIONAL AYURVEDA DAY celebration. More than 450 delegates attended the conference which included Ayurveda graduates, post graduates and faculty members from 6 different states.
Institute also organised a preconference workshop on 24th October 2018 in association with Divisional Food Laboratory Belgaum division, Belagavi, Government of Karnataka on Vishakta Ahara Pariska. Mr. Lingappa B, Chief Food Analyst, deliberated on present adulteration menace in India and demonstrated about 30 different adulteration detection tests that can be performed easily with minimum requirements. Delegates were given hands on training and Manual of Adulteration Detection Test to inculcate to their colleges.

Keynote Address
Dr. B. Sreenivas Prasad, Principal, KAHER’S Shri. B. M. K. Ayurevd Mahavidyalaya, Belagavi expressed his views about Agadatantra.  He highlighted Agadatantra as futuristic Ayurveda Specialty and stressed on the need for the research in the subject. He gave insights on the past visha examination methods done on animals as part of cultural practices in dogs, peacock and obligation given to fire deity.[1] He proposed the route-map to establish new horizons by working in domains of disorders caused by food style and human induced toxin food chain. He emphasized few studies done at institute level like how five minutes Haridra jala (Turmeric water) wash had shown reduction in pesticides level in common vegetable[2] and another study of jalanirvishikarana yoga (ancient water purification method) significantly reduced microbial load and increase in biological oxygen demand[3]. He called on the gathering to work on such simple practices which could serve society at large.

Plenary sessions 
Dr C D Sahadevan, Dhanwantari Vaidyasala, Thodupuzha, Kerala spoke over Understanding and Utilisation of Agadatantra Principles in Oncology Practice. Understanding cancer on the basis of Ayurveda fundamentals by corroborating the presented cancer symptoms with dosha and their elucidation on present day investigations like LDH enzyme, triglycerides, IgE, tumor markers and even blood components against vata, pitta and kapha. Based on his empirical Ayurveda understanding, cancers like acute and chronic leukaemias, Ca lung, Ca uterus and Hepatocellular cancers can be managed successfully for giving quality of life and restrain disease progression at acceptable rate. Concepts of siraja granthi, visarpa, vishopta, apachi, gandamala, kshataja kasa and few other conditions can be considered under umbrella of cancer. He also explained about samprapti developed in real case scenery and treatment principles adopted like langhana,  jwara chikitsa, visha chikitsa, sthanika chikitsa like lepa on breast cancer, modulated matra basti’s or panchkarma in Non-Hodgkin’s lymphoma. He enlisted the formulations in practice for cancer like Shandagapaneeya, Nirgundyadi kashaya, Patolakaturohinyadi kashaya, Draksharista, Patoladi kashaya, Dashanga agada, Mahamanjistadi kashaya, Nayopayam kashaya, Panhagavya ghrita, Gandaka rasayana, Paranthyadi tail for application, utilization of single dravya like Karanja patra swarasa in Uterus cancer.
Dr. Gopikrishna S Assistant prof. Dept. of Agadatantra, Vaidyaratnam P S Varrier Ayurveda College, Kottakkal, Kerala elaborated about diagnosis of the bite, Post snake bite skin manifestations and wound complications. Sir presented several successful cases with treatment based on dosha analysis and stressed on more of drusta karma (practical experience leading to clinical acumen). He also highlighted several formulations like Jeevaraksha agada, Tarunabhaskara Agada, Erytaila etc. from Kerala’s traditional practices[4].
Vaidya Brahamdattan Nambuthiri, Ullanoor Mana, Venkitangu, Thrissur, Kerala highlighted theoretical and practical aspect of Keraliya Visha Chikitsa. He contextualised the visha chikitsa from traditional texts like Visha Jyothsnika, Paryoga sammuchaya. He explained about Dhatugata visha lakshana, diagnosis and its management by special treatments of Keraleeya Visha Chikitsa like Ootha, Kizhi (sweda), ghrita dhaara etc. He highlighted several sacred formulations like Vishahaari leha used to diagnose type of bite. He showed several cases treated with Mruta sanjeevini vati, Hingwadi vati, Mrutasanjeevini Anjana, Garudanjana & Churn Raja anjana. He also highlighted various cases of lootha visha and Vruschika visha conditions. Finally he also expounded visha upadravas and their management.
Dr. C.M. Sreekrishnan, Director, Dhanwantari Institute of Dermatology, Nelluvai, Thrissur, Kerala He explained about different Balavisarpa with names, clinical images, differential diagnosis on dosha and its identical conventional diagnosis (eg. Vishaja visarpa to Epidermosis bullae). Successively explained management of 51 types of Balavisarpa based on Agadatantra principles.[5]
strong>Dr Muralidharan A K, Principal, M.V.R. Ayurveda Medical College, Parassinikkadavu, Kannur, Kerala, spoke on Agadayogas practically & successfully used in the management of post snake bite complications. He explained snake bite complications under three categories as Immediate, Intermediate and delayed complications. Formulations like Jeevaraksha Agada (Gulika) & Tarunabhaskara Agada along with their ingredients, method of preparation and administration in immediate stage was showcased. Intermediate complications like renal failure, haematological disruptions like clotting  in case of Viper bites, its management with the use of Agadas along with Kashayas like Punarnavadi, Patolakaturohinyadi, Amritottara and few others was explained. Non healing ulcers, Altered Sensation of taste & Psychosomatic manifestation were explained as delayed complications and their management through Aragwadadi Kashayam, Manjishtadi Kashayam, Nalpamaram Kashayam, Triphala Kashayam, Patola Katurohinyadi Kashayam, Jathyadhi Ghritham & Murivenna taila for external applications was demonstrated through treated cases. He also highlighted yogas like Visha Bilwadi, Bilwadi agada, Chandraprabha vati, Lodhrasevyaadi kashayam, Sigrupunarnavadi choornam & Sarivadya choornam along with their ingredients and therapeutic use.
Dr. Vikas D. Dighe, Scientist ‘E’ and Head, National Center for Preclinical Reproductive and Genetic Toxicology; ICMR-National Institute of Research in Reproductive Health, Parel, Mumbai dealt on Geno-toxicity caused by Environmental and Occupational toxins.  He explained about the known pathways like Endocrine disruption[6]. He added to presentation that Environmental toxins can also act as Carcinogens and they are categorized as Non-genotoxic carcinogens and Genotoxic carcinogens. He presented multiple studies showing DNA level damages identified through DNA adduct analysis, DNA strand breakage, Unscheduled DNA synthesis (UDS), Sister chromatid exchange, Chromosome aberration analysis, Micronucleus analysis etc. Finally he touched over heavy metal toxicity and its mechanism leading to mutagenicity along with methods of detection for it. [7]
Dr. Dhananjay Mhasade, BAMS, D.A.M, LLB, a famous Medico-legal expert in the field of Ayurveda dealt in detail about the Medico-legal Aspects in Ayurveda Clinical Practice. He presented current importance of Medical Negligence in clinical practice. He said that due to increased access to the medical and legal knowledge to the general public there is need for proper execution of professional duties.  He raised the consensus about legal aspects of the registration, nomenclature of Degrees, Advertising of clinic and hospital etc. He stressed on discharge of Professional duties and how it helps to overcome any chances of Professional/Medical Negligence. He also briefed with Ayurveda contexts relating to writing of a proper and legally acceptable prescription, educating patients about DO’s and DON’T’s which usually goes unsaid. He sensitised delegates about Bio-medical waste in Ayurveda, Consent, Issuing of Medical Certificates and Registration of clinic/Hospital, Medical documents and Medical records. Lastly he highlighted about probable Medical negligence that can happen with Panchakarma with few examples and explained about few acts like Indemnity act etc. He concluded his talk by saying that skilful discharge of Professional duties and Proper documentation can prevent any kind of Medical Negligence and they only can protect the Physician.
Dr. Rudramma R Hiremath, KAHER’s Shri. B. M. K. Ayurved Mahavidyalaya, Belgavi  presented studies of Mercury, Lead and Arsenic, major heavy metals done through X-ray diffraction, Scanning Electron Microscopy, X-ray photoelectron spectroscopy, Energy dispersive X-ray Analysis & in vitro. She also detailed updates on the studies done on Kajjali, Rasasindhura, Naaga bhasma.
Dr. Mahesh P Savalagimath, KAHER’s Shri. B. M. K. Ayurved Mahavidyalaya, Belgavi  presented on the Application and Rationality of Agada principles in Dermatological manifestations. He explained in detail about the aetiology and nature of present day skin diseases and stressed about bringing Etiological diagnosis in clinical practice. He concentrated on utilization of Dashanga Agada, Bilwadi Agada and Dooshivishari agada which are available for practice. He elaborated on how and when to use these Agadas. He highlighted about the rationality behind selection of various agadas, their dose, and duration and also about choosing suitable shaman kashayas.
Dr. Vedantam Giridhar, KAHER’s Shri. B. M. K. Ayurved Mahavidyalaya, Belgavi  discussed about the Exploring research opportunities in Agadatantra. He highlighted the Toxicity Testing Guidelines for Ayurveda and necessity of Toxico-Pharmacology studies. He strongly proposed to explore Agada’s Distribution, Metabolism, Excretion Kinetics and action at Cellular, Biochemical and Molecular levels[8][9]. He also recommended use of Bioinformatics for planning the studies[10]. He instilled new thoughts for developing newer study models on the grounds of Ayurveda and Agadatantra principles for proper research.
Dr. Mahadev B Gundakalle, KAHER’s Shri. B. M. K. Ayurved Mahavidyalaya, Belgavi discussed about the research updates in Agadatantra done on Bilwadi Agada, Dooshivishari Agada, Moorvadi Agada, Sindhuvaradi Agada, Panchashireesha Agada and Malatyadi agada in area of Hepatoprotective activity, Nephroprotective activity, cardio protective activity etc. Sir went on to discuss about studies on Ethno practices and environmental toxicology.
Dr Santosh F Patil, KAHER’s Shri. B. M. K. Ayurved Mahavidyalaya, Belgavi explained utilization of current technology in Agadatantra research that can be adopted for exploring visha pharmacology, pathology, sign and symptomatology. Different equipments like HPTLC, Infrared Spectroscopy, LC-MS, Gel-electrophoresis, NMR, MALDI-TOF, Microarray, Databases (TOXINPRED etc.) and domains like transcriptomics, proteomics and metabolomics were explained with examples [11]. He explained different studies done across scientific community to highlight technology importance in relation to Agadatantra, to mention one is Effect of Shodhana on Vatsanabha[12] and Kupeelu[13] elicited by HPTLC and Infrared Spectroscopy showing change in percentage of active toxic components. He highlighted how techniques in animal studies have given insight to the different chemicals like oestrogen compounds being used can affect over psychological plane[14] proving garavisha lakshanas. He also showed how studies done on Ashwaganda[15] and plumbagin as a crude drug and extract differ in therapeutic pathway.
Dr. Shrutika S Karoshi, KAHER’s Shri. B. M. K. Ayurved Mahavidyalaya, Belgavi explained about Garbhasthapana effect of Dooshivishari Agada. She specified increasing incidence of spontaneous abortions and congenital malformations with its relation to teratogens; their mechanisms and effects. Also discussed how we can incorporate Ayurvedic phenomenon of garbhopaghatakara bhavas and its treatment to minimize effects of teratogens based on experimental studies conducted on different models of reproductive toxins and teratogens by using Dooshivishari agada. She highlighted the encouraging results of improved estrous cycle; semen quality may it be motility or count in rats. She also explained teratogenicity study (unpublished data) of 1st and 2nd generations where intervention is done by Dooshivishari agada, showed litter size was increased, number of resorptions was reduced and also malformations were prevented.
National Conference was able to meet its objectives to disseminate the Agadatantra practice adopted in different diseases and conditions such as dermatology, autoimmune disorders and cancer. It was able to strengthen the practice of agadatantra in Animate poisoning like utilisation of different therapeutics like oota chikithsa, mruta sanjeevani, nasya and anjana. These can be used as atyayika kriya’s in Visha chikithsa in present era but we need  to be provide proper theoretical and clinical exposure. It has built consensus on new research areas with existing technology for Agadatantra and opened new avenues for collaboration as training centres of Agadatantra. Experts also expressed consensuses on present importance of Ayurveda Medico-legal aspects at different levels like drugs, practice and management of hospitals.

References

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  2. Dhiman A, Hiremath S K, a comparative study of effect on Brassica Oleracea Linn (Cauliflower) using diffrent washing methods w.s.r to estimation of pesticide residue. SPICE project under VGST, Govt. of Karnataka. Submitted to KLE University,2013-14.
  3. An Experimental Study on the Efficacy of Vagbhatoka Jala Nirvishikarana yoga on Polluted Water, by Dr Shivanand Kalasannavar & Dr SK Hiremath, PG Dissertation submitted to KLE University, 2013
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